Shibatomi, Kazutaka
| Affiliation | Institute for Research on Next-generation Semiconductor and Sensing Science (IRES²) |
|---|---|
| Concurrent post | Department of Applied chemistry and Life Science |
| Title | Professor |
| Fields of Research | Synthetic Organic Chemistry / Organo Metallic Chemistry / Fluorine Chemistry |
| Degree | Ph. D (Nagoya City University) |
| Academic Societies | The Chemical Society of Japan / The Pharmaceutical Society of Japan / The Society of Synthetic Organic Chemistry, Japan / The Society of Fluorine Chemistry, Japan / American Chemical Society |
| shiba@chem Please append ".tut.ac.jp" to the end of the address above. |
|
| Laboratory website URL | http://chem.tut.ac.jp/orgchem/ |
| Researcher information URL（researchmap） | Researcher information |
Research
1) Efficient Synthesis of Fluorinated Organic Molecules
2) Design and Synthesis of New Chiral Catalysts
Selected Publications:
◆ K. Shibatomi
"Organocatalytic Synthesis of Chiral Halogenated Compounds"
The Chemical Record, 2023.
◆ H. Mizutani, R. Kawanishi, K. Shibatomi
"Enantioselective Decarboxylative Protonation and Deuteration of β-Ketocarboxylic Acids"
Chemical Communications, 2021, 57(54), 6676-6679.
◆ R. Kawanishi, K. Nakada, K. Shibatomi
"Decarboxylative trifluoromethylthiolation of pyridylacetates"
Beilstein Journal of Organic Chemistry, 2021, 17, 229-233.
◆ M. K. Kam, A. Sugiyama, R. Kawanishi, K. Shibatomi
"Asymmetric Synthesis of Tertiary α-Hydroxyketones by Enantioselective Decarboxylative Chlorination and Subsequent Nucleophilic Substitution"
Molecules, 2020, 25, 3902.
◆ R. Kawanishi, S. Hattori, S. Iwasa, K. Shibatomi
"Amine-Catalyzed Decarboxylative Aldol Reaction of β-Ketocarboxylic Acids with Trifluoropyruvates"
Molecules, 2019, 24, 2773.
◆ R. Kawanishi, L. Phongphane, S. Iwasa, K. Shibatomi
"Decarboxylative Fluorination of 2-Pyridylacetates"
Chemistry A European Journal, 2019, 25(31), 7453-7456.
◆ A. Naruse, K. Kitahara, S. Iwasa, K. Shibatomi
"Synthesis of α-Fluoroenones by Elimination of α-Chloro-α-fluoroketones"
Asian Journal of Organic Chemistry, 2019, 8(5), 691-693.
◆ M. Katada, K. Kitahara, S. Iwasa, K. Shibatomi
"Catalyst-Free Decarboxylative Fluorination of Tertiary β-Keto Carboxylic Acids"
Synlett, 2018, 29(18), 2408-2411
◆ K. Shibatomi, K. Kitahara, N. Sasaki, Y. Kawasaki, I. Fujisawa, S. Iwasa
"Enantioselective decarboxylative chlorination of β-ketocarboxylic acids"
Nature Communications, 2017, 8, 15600.
◆ K. Shibatomi, K. Kitahara, T. Okimi, Y. Abe, S. Iwasa
"Enantioselective fluorination of α-branched aldehydes and subsequent conversion to α-hydroxyacetals via stereospecific C-F bond cleavage"
Chemical Science, 2016, 7(2), 1388-1392.
◆ K. Shibatomi, M. Kotozaki, N. Sasaki, I. Fujisawa, S. Iwasa
"Williamson Ether Synthesis with Phenols at a Tertiary Stereogenic Carbon: Formal Enantioselective Phenoxylation of β-Keto Esters"
Chemistry-A European Journal, 2015, 21(40), 14095-14098.
◆ K. Shibatomi, Y. Kawasaki, S. Iwasa
"Organocatalytic Enantioselective Diels-Alder Reaction of 4,4,4-Trifluorocrotonaldehyde"
Journal of Fluorine Chemistry, 2015, 179, 77-82.
◆ K. Shibatomi
"Catalytic Enantioselective Constructions of Trifluoromethylated Chiral Stereogenic Centers via the Conjugate Addition to CF3-Alkenes: Overview of Current Progress"
Current Organic Chemistry, 2015, 19(16), 1619-1637.
◆ K. Shibatomi
"Highly Enantioselective Synthesis of Halogenated Compounds Utilizing Lewis Acid or Organocatalyst"
Journal of Synthetic Organic Chemistry, Japan, 2014, 72(3), 232-245.
◆ K. Shibatomi, T. Okimi, Y. Abe, A. Narayama, N. Nakamura, S. Iwasa
"Organocatalytic asymmetric fluorination of α-chloroaldehydes involving kinetic resolution"
Beilstein Journal of Organic Chemistry, 2014, 10, 323-331.
◆ K. Shibatomi, A. Narayama
"Catalytic Enantioselective α-Chlorination of Carbonyl Compounds"
Asian Journal of Organic Chemistry (Review), 2013, 2(10), 812-823.
◆ A. Narayama, K. Shibatomi, Y. Soga, T. Muto, S. Iwasa
"Copper(II)-Catalyzed Enantioselective Fluorination of β-Keto Esters Using Chiral Spiro Oxazoline Ligands"
Synlett, 2013, 375-378.
◆ K. Shibatomi, Y. Soga, A. Narayama, I. Fujisawa, S. Iwasa
"Highly Enantioselective Chlorination of β-Ketoesters and Subsequent SN2 Displacement of Tertiary Chlorides: A Flexible Method for the Construction of Quaternary Stereogenic Centers"
Journal of the American Chemical Society, 2012, 9836-9839.
◆ K. Shibatomi, A. Narayama, Y. Abe, S. Iwasa
"Practical Synthesis of 4,4,4-Trifluorocrotonaldehyde: A Versatile Precursor for the Enantioselective Formation of Trifluoromethylated Stereogenic Centers via Organocatalytic 1,4-Additions"
Chemical Communications, 2012, 7380-7382.
◆ K. Shibatomi, F. Kobayashi, A. Narayama, I. Fujisawa, S. Iwasa
"A Diels-Alder Approach to the Enantioselective Construction of Fluoromethylated Stereogenic Carbon Centers"
Chemical Communications, 2012, 413-415.
◆ K. Shibatomi, A. Narayama, Y. Soga, T. Muto, S. Iwasa
"Enantioselective gem-Chlorofluorination of Active Methylene Compounds Using a Chiral Spiro Oxazoline Ligand"
Organic Letters, 2011, 2944-2947.
◆ K. Shibatomi, K. Futatsugi, F. Kobayashi, S. Iwasa, H. Yamamoto
"Stereoselective Construction of Halogenated Quaternary Stereogenic Centers via Catalytic Asymmetric Diels-Alder Reaction"
Journal of the American Chemical Society, 2010, 5625-5627.
◆ K. Shibatomi
"Alternative Synthetic Strategies for Enantioselective Construction of Halogenated Chiral Carbon Centers"
Synthesis (Review), 2010, 2679-2702.
◆ K. Shibatomi, T. Muto, Y. Sumikawa, A. Narayama, S. Iwasa
"Development of a New Chiral Spiro Oxazolinylpyridine Ligand (Spymox) for Asymmetric Catalysis"
Synlett, 2009, 241-244.
◆ K. Shibatomi, Y. Tsuzuki, S. Iwasa
"Lewis Acid-catalyzed Asymmetric Fluorinations of β-Keto Esters: Dramatic Improvement in Enantioselectivity by Changing the Operation Sequence"
Chemistry Letters, 2008, 1098-1099.
◆ K. Shibatomi, Y. Zhang, H. Yamamoto
"Lewis Acid Catalyzed Benzylic Bromination"
Chemistry-An Asian Journal, 2008, 1581-1584.
◆ K. Shibatomi, H. Yamamoto
"Stereoselective Synthesis of α,α-Chlorofluoro Carbonyl Compounds Leading to the Construction of Fluorinated Chiral Quaternary Carbon Centers"
Angewandte Chemie International Edition, 2008, 5796-5798.
◆ K. Shibatomi, Y. Tsuzuki, S.-I. Nakata, Y. Sumikawa, S. Iwasa
"Synthesis of Axial Chiral Cyclic Amine Substituted 2-(Oxazolinyl)pyridine Ligands for Catalytic Asymmetric Fluorination of β-Ketoesters"
Synlett, 2007, 551-554.