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Hirose, Yuu

Affiliation Department of Applied chemistry and Life Science
Title Assistant Professor
Fields of Research Genome Biology, Photobiology
Degree Science (The Univ. of Tokyo)
Academic Societies Society of Genome Microbiology of Japan, The Japanese Society of Photosynthesis Research, The Japanese Society of Plant Physiologists, Japanese Society of Microbial Ecology, The Biophysical Society of Japan
E-mail hirose@chem
Please append ".tut.ac.jp" to the end of the address above.
Researcher information URL(researchmap) Researcher information

Theme1: Light Absorption Mechanism of Tetrapyrrole-binging Proteins

Overview

Photosynthetic organisms utilize various kinds of pigment for their photochemical reactions such as photosynthesis and photosensing etc. Cyanobacteria harbor unique phychrome-related photoreceptors that are called "cyanobacteriochromes" (Ikeuchi and Ishizuka et al 2008 Photochem. Photobiol. Sci.). I discovered that green/red cyanobacteriochromes change protonation state of the tetrapyrrole chromophore, which is designated to a "protochromic photocycle" (Hirose et al 2013 PNAS). I am now working on the effect of protonation state on the state of p-electrons of cyanobacteriochromes and other tetrapyrrole-binding proteins.

Theme2: Analysis of Complementary Chromatic Acclimation Process of Cyanobacteria

Overview

While plants utilize blue and red light for photosynthesis, cyanobacteria utilize green to orange region of the spectrum in addition to blue and red light . It is well known that certain cyanobacteria change their light harvesting pigments, green-absorbing phycoerythrin and red absorbing phycocyanin, a phenomenon which is called " complementary chromatic acclimation" . I discovered that green-activated CcaS/CcaR system regulate a group II chromatic acclimation species (Hirose et al 2008 PNAS, Hirose et al 2010 PNAS), which contrasts red-activated RcaE/RcaF/RcaC system for group III species (Kehoe et l 1996 Science). I am interested in the evolution from CcaS/CcaR system to RcaE/RcaF/RcaC system.

Theme3: De novo Sequencing and Transcriptome Analysis of Cyanobacteria

Overview

Emerging of the next generation sequencer enables us to analyze non-model cyanobacterial species. I am managing three types of NGS, GS 454FLX+ (Roche), Ion Proton (Life tech.) and Miseq (illumine), in Toyohashi Univ. of Tech. I perform de novo sequencing and transcriptome analysis of various kinds of non-model cyanobacteria.


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