A Semiconductor Chip Detects Antigen Concentrations at 1 Parts per Quadrillion Molar Mass
01 Dec 2020
For use as an at-home IoT biosensor
Associate Professor Kazuhiro Takahashi and Assistant Professor Yong-Joon Choi of the Department of Electrical and Electronic Information Engineering at Toyohashi University of Technology have developed a chip that can sense antigens at one part per quadrillion molar mass. The chip was created using semiconductor micromachining technology. Antigens derived from diseases and present in blood and saliva were adhered onto the surface of a flexibly deformable nanosheet. The amount of force generated during the interaction between adhered antigens was then converted into nanosheet deformation information in order to successfully detect specific antigens. Created with semiconductor technology machined at the millimeter scale, this sensor chip is expected to contribute to telemedicine by functioning as an IoT biosensor that allows antigen and antibody tests to be carried out from home.