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Takeshi Kawano

Affiliation Department of Electrical and Electronic Information Engineering
Title Associate Professor
Fields of Research Micro/Nano Devices, Neural Interface Devices
Degree Ph. D. (Toyohashi University of Technology)
Academic Societies IEEE(EDS)
E-mail kawano@ee
Please append ".tut.ac.jp" to the end of the address above.
Laboratory website URL http://www.int.ee.tut.ac.jp/icg/member/~takekawano

Research

Takeshi Kawano received the M.S. degree in Electrical and Electronic Engineering in 2001, and Ph.D. degree in Electronic and Information Engineering in 2004, all from Toyohashi University of Technology, Aichi, Japan. Since 2004, he was a postdoctoral research fellow at Toyohashi University of Technology, where he worked on the development of silicon microprobe array devices for neural recordings. He joined Mechanical Engineering and Berkeley Sensor and Actuator Center (BSAC) at the University of California Berkeley on April 2005, as a postdoctoral researcher with his funding from the Japan Society for the Promotion of Science (JSPS). Takeshi Kawano joined the faculty of Toyohashi University of Technology on May 2007, where he is currently an associate professor of Electrical and Electronic Information Engineering. He is also a researcher of Precursory Research for Embryonic Science and Technology (PRESTO), funded by the Japan Science and Technology Agency (JST), from October 2010.

Kawano's present research interests focus on the fabrication of micro/nanoscale devices especially microprobes, nanowires and nanotubes, and the manufacturing of integrated circuits with sensors as well as the sensor devices to use in neural interfaces (neurons-electronics interface device). His research has been recognized with many awards including, IEEE International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) Outstanding Paper Award (2009), 2008 Highlights Collection (JMM)(2009), IOP Select (2008), IEEE Electron Device Japan Chapter Student Award (2005), JSPS Postdoctoral Fellowship for Research Abroad (2004) and Japan Society of Applied Physics (JSAP) Presentation Award (2001).

Theme1:Neural interface devices

Overview

Very fine needle-electrode arrays potentially offer both low invasiveness and high spatial resolution of electrophysiological neuronal recordings in vivo. We have developed silicon-growth-based three-dimensional microscale-diameter needle-electrodes arrays. The fabricated needles exhibit a 3-μm-diameter tip and a 210-μm length. Due to the microscale diameter, our silicon needles are more flexible than other microfabricated silicon needles with larger diameters. The needles can penetrate into the whisker barrel area of a rat’s cerebral cortex, and detect the neuronal action potentials. Compared to conventional electrodes with large needle diameters (~100 μm), the clear advantage is that our device with microscale diameter needles reduces the kill zone for neural recordings. Moreover, the fabrication technology can be applicable to realize numerous devices including microtube for drug delivery and optical fiber for optogenetic applications, enhancing the performance of microdevices in fundamental neuroscience and medical applications.

Selected publications
A. Fujishiro, H. Kaneko, T. Kawashima, M. Ishida, and T. Kawano, "In-vivo neuronal action potential recordings via three-dimensional microscale needle-electrode arrays, Scientific Reports, Vol. 4, No. 4868, May 2014.
M. Sakata, T. Nakamura, T. Matsuo, A. Goryu, M. Ishida, and T. Kawano, "Vertically integrated metal-clad/silicon dioxide-shell microtube arrays for high-spatial-resolution light stimuli in saline, Applied Physics Letters, Vol. 104, 164101, April 2014.

Keywords

Neural interface device, ultrasmall neuroprobe-microelectrode array, drug delivery system, optogenetics, microelectronics, brain-machine interface

Theme2:Nanoscale neurorpbes

Overview

Nanoscale devices have the potential to measure biological tissues as well as individual cells/neurons. However, three-dimensional (3D) multi-site probing remains problematic because only planar-type device designs are applicable to sample surfaces. We have developed 3D nanoscale electrode tipped microwire arrays with high aspect ratios. As a promising device application, we have demonstrated the trapping of nanoparticles and the particle injection into a soft material, demonstrating a multi-site wide-area batch depth injection. Such nanotip wire arrays should be applicable to trap numerous particles, including DNA/molecules, and may realize injection into biological tissues and individual cells/neurons. We are also currently developing nanoscale probe-electrode arrays for multi-site intracellular recordings within a tissue.

Selected publications
A. Goryu, R. Numano, A. Ikedo, M. Ishida, and T. Kawano, "Nanoscale tipped microwire arrays enhance electrical trap and depth injection of nanoparticles, Nanotechnology, Vol. 23, No. 41, 415301, September 2012.
A. Goryu, A. Ikedo, M. Ishida, and T. Kawano, "Nanoscale sharpening tips of vapor-liquid-solid grown silicon microwire arrays, Nanotechnology, Vol. 21, No. 12, 125302, March 2010.

Keywords

Intracellular probe, nanowire, nanoinjection

Theme3:Integration of Mirco/Nano devices

Overview

We have shown both gas pressure and species sensing capabilities based on the electrothermal effect of a multi-walled carbon nanotube (MWCNT). Upon exposure to gaseous environments, the resistance of a heated MWCNT is found to change following the conductive heat transfer variances of gas molecules. To realize this mechanism, a suspended MWCNT is constructed by synthesis and assembly in localized chemical vapor deposition. Vacuum pressure sensitivity and gas species differentiability are observed and analyzed. Such MWCNT electrothermal sensors are compact, fast and reversible in responses, and fully integratable with microelectronics (UC Berkeley Prof. Lin).

Selected publications
T. Kawano, H. Chiamori, M. Suter, Z. Qin, B. Sosnowchik, and L. Lin, "An electrothermal carbon nanotube gas sensor, Nano Letters, Vol. 7, No. 12, pp. 3686-3690, December 2007.
T. Kawano, D. Christensen, S. Chen, C. Y. Cho and L. Lin, "Formation and characterization of silicon/carbon nanotube/silicon heterojunctions by local synthesis and assembly, Applied Physics Letters, Vol. 89, 163510, October 2006.

Keywords

Integrated circuit, microelectromechanical systems (MEMS), nanotechnology

Title of class

Mathematics IV (B01310960)
Semiconductor Electronics II (B01320980)
Micro/Nano Systems (M22623040)


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